Sam Altman, CEO of Open AI, spoke publicly about how a single weekend with ayahuasca had a profound improvement on his mental health and creativity. He’s the latest high-profile CEO to break the stigma of sharing how psychedelic drugs are being leveraged in a competitive business landscape. Despite the overwhelming endorsements and positive press coverage, bringing psychedelics into the workplace can also have unintended consequences. Come curious and ready to learn; psychedelics are going mainstream. As business leaders, it’s imperative that we understand guidelines and guardrails of psychedelic leadership development.